They say imitation is the sincerest form of flattery. The field of optogenetics has taken that motto to heart and paid photosynthetic algae an immense complement. It’s actually very common for science and engineering technology to take a hint from nature, but in this case that hint was actually entire gene sequences. Channelrhodopsins are a group of proteins found in some photosynthetic algae which directly regulate the flow of ions through membranes. I’ve talked about channel proteins before and how their activity can be modulated by either chemical or electrical signals, but these channelrhodopsins are special because they are activated by light. The discovery of the genes that code for these proteins and the genetic engineering that has introduced these genes into mammalian cells has spurred research in the area called optogenetics . Perhaps most famously, optogenetics has been applied to neuroscience with the transfection of neurons with the channelrhodopsin gene. A ...
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